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Sepsis is one of the most common, least-recognized illnesses
Every three seconds, someone dies of sepsis. We're working to reduce that number by 20% by 2020.
20,000,000-30,000,000 people around the world are afflicted every year. Over 6 million of them are infants or small children, and over 100,000 are new mothers. Sepsis is the leading cause of death by infection in the world – despite modern vaccines, antibiotics, and intensive care. And the incidence of sepsis continues to increase dramatically. Hospitalizations for sepsis have more than doubled over the last 10 years; today, more people are hospitalized for sepsis than for heart attack.

We in the Global Sepsis Alliance have come together to raise the public and professional profile of sepsis - a problem that is common, global in scope, and devastating in its consequences. This devastating impact of sepsis we have witnessed is what has led us to initiate the World Sepsis Day. We know the toll of sepsis can be reduced, but we recognize that a major barrier to success lies in the fact that sepsis is largely unknown to the public, and poorly understood by professionals. Too many people develop sepsis. Too few survive. We will change this.

Reduce the incidence of sepsis through effective prevention strategies
We’re working to achieve that by mobilizing stakeholders to ensure that prevention and control strategies target those who are most in need. We encourage the implementation of international sepsis guidelines to enable healthcare workers to recognize sepsis earlier, and treat it more effectively. We’re also working to raise awareness of sepsis, as well as political support to place sepsis firmly on the development agenda and make the disease a priority for clinical improvement.

Sepsis survival will increase for children (including neonates) and adults in all countries through the promotion and adoption of early recognition systems and standardized emergency treatment.

We’re working to make adequate prevention and therapy programs available to people around the world by 2020. By promoting good general hygiene practices like proper hand hygiene and clean birthing conditions, as well as improvements in sanitation and nutrition, access to clean water, and vaccination programs for specific patient populations, we aim to reduce the global incidence of sepsis by at least 20% by 2020.

If sepsis is recognized and treated within the first hour, the chance of survival is over 80%. Widespread effective early-recognition and treatment systems are critical to increasing sepsis survival rates.

We aim to increase sepsis survival rates by 10% over their 2012 levels. These figures must be monitored and documented by sepsis registries, and build upon improvements already achieved following the launch of the Surviving Sepsis Campaign and the International Pediatric Sepsis Initiative.

In accordance with international consensus guidelines, all countries must monitor the time it takes for sepsis patients to receive the most important basic interventions, like antimicrobials and intravenous fluids.

Provide better access to suitable rehabilitation services for people everywhere
We’re working to ensure that by 2020, all member countries have dedicated resources and established standards for adequate follow-up treatment for sepsis survivors following hospitalization.

Increase awareness and understanding of sepsis among healthcare professionals
and the general public
We want sepsis to be a household word by 2020, one synonymous with the need for emergency intervention.

We’re working to educate lay people everywhere to understand the early warning signs of sepsis, and to encourage families to routinely question any delays in healthcare delivery. Adequate treatment and rehabilitation facilities with well-trained staff must be made available for both acute and long-term care of sepsis patients.

We’re also working to establish training standards for sepsis as a medical emergency to ensure that healthcare professionals act promptly and effectively.

Track and measure the global burden of sepsis and the positive impact of sepsis control and management interventions
All member countries will establish consistent sepsis registries that meet international data requirements and standards. Together we can decrease the global impact of sepsis.
… Please sign our declaration and join us in the fight against this disease.

Source 8_ Kumar A, Roberts D, Wood KE, et al.: Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med, 34: 1589-1596, 2006.
Over the past year we've been collecting the questions we receive most frequently about sepsis. Please share this information with your friends and family. Don’t see your question on the list? Get in touch with us, and we’ll do our best to help.
Sepsis Facts
Sepsis is common and often deadly. It remains the primary cause of death from infection, despite advances in modern medicine like vaccines, antibiotics, and intensive care.
What is sepsis
Pat had a pneumococcus sepsis because he lost his spleen after a car accident as a teenager. He experienced multiple organ failure, followed by critical illness polyneuropathy.
How to prevent sepsis
Sepsis is always caused by an infection, most often by bacteria, but sometimes by fungi or protozoa (such as malaria). That means that preventing infection is one of the best ways to prevent sepsis.
Suspect sepsis
If you, a relative, or a patient feels "severely sick", "that something is wrong", or "are not yourself", and shows any of the following symptoms, you should suspect sepsis: